产品货号：
Z38140
中文名称：
ESRP1/2抗体
英文名称：
Anti-ESRP1/2 Antibody(Clone#23A7.C9)
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ESRP1/2 Antibody (Clone#23A7.C9) |
| 指标别名 | Esrp1/2;Esrp1;Ersp2;Rbm35a;Epithelial splicing regulatory protein 1;RNA-binding protein 35A;RNA-binding motif protein 35A;RNA-binding protein 35B;RNA-binding motif protein 35B |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | WB |
| 基因名称 | ESRP1/ESRP2 |
| 克隆号 | 23A7.C9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Anti-Esrp-1/2 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein. |
| 计算分子量 | 76kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This antibody was purified from tissue culture supernatant by Protein-A chromatography followed by extensive dialysis against the buffer stated above.This antibody reacts with both mouse Esrp-1 and Esrp-2 proteins.A BLAST analysis of the immunizing protein sequence shows 100% homology with Esrp-1 from mouse and a 91% sequence homology with Esrp-1 from human,pig,rat,opossum,horse,cattle,panda,dog,and chimpanzee.The binding epitope of this monoclonal antibody has not been mapped. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Epithelial splicing regulatory protein-1 (Esrp-1) and Esrp-2 are mRNA splicing factors that regulate the formation of epithelial cell-specific isoforms.They specifically regulate the expression of FGFR2-IIIb,an epithelial cell-specific isoform of FGFR2,and also regulates the splicing of CD44,CTNND1,ENAH,3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT).Esrp-1 and -2 act by directly binding specific sequences in mRNAs.They bind the GU-rich sequence motifs in the ISE/ISS-3,a cis-element regulatory region present in the mRNA of FGFR2. |
| Uniprot ID | Q8K0G8 |
| 基因名全称 | Epithelial splicing regulatory protein 1 |
| 推荐稀释比 | ELISA:1:750,000 WB:1:1000 |
相关搜索：ESRP1/2抗体，ESRP1抗体，ESRP2单抗，Anti-ESRP1/2 Antibody(Clone#23A7.C9)